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Tag: Blood-brain barrier

April 4, 2022 Drug delivery / Pharma applications

Computational Modeling on Binding Interactions of Cyclodextrins with the Human Multidrug Resistance P-glycoprotein

Molecular docking approaches and DFT ab initio simulations were combined for the first time, to study the key interactions of

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August 25, 2021 Drug delivery / Pharma applications

Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

Quercetin, a flavonoid with possible neuroprotective action has been recently suggested for the early-stage treatment of Alzheimer’s disease. The low

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September 3, 2020 Drug delivery / Pharma applications

Delivering Crocetin across the Blood-Brain Barrier by Using γ-Cyclodextrin to Treat Alzheimer’s Disease

Scientific report has published a paper on γ-cyclodextrin-enabled crocetin formulation which can deliver crocetin into the brain. [1] Crocetin (CRT)

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July 10, 2020 Drug delivery / E-ducation / Pharma applications

Book: Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of

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September 22, 2018 CD as API / Pharma applications

Therapeutic potential for cyclodextrin‐based macromolecular systems in NPC

A paper has just come out in Macromolecular Rapid Communications highlighting the potential benefits of cyclodextrin-based macromolecular systems as cholesterol-mopping

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July 31, 2018 CD as API / Pharma applications

HPBCD can cross the Brain-Blood Barrier

Matencio et al. reported in their recent paper that 92.8% of HPBCD administered intrathecally to a child suffering from Niemann

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Recent Posts

  • V International Summer School on Cyclodextrins
  • Recent important review articles from Thorsteinn Loftsson’s group about ophthalmic drug delivery
  • Application of cyclodextrin containing sliding-ring polymers in oil-well cement
  • Oligomer Sensor Nanoarchitectonics for “Turn-On” Fluorescence Detection of Cholesterol at the Nanomolar Level
  • CIDALTEX® ANTIVIRAL MASKS DURING THE COVID-19 PANDEMIC

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Top Posts

  • Recent important review articles from Thorsteinn Loftsson's group about ophthalmic drug delivery
  • V International Summer School on Cyclodextrins
  • Alpha-CD powder and tablets in Japan
  • CIDALTEX® ANTIVIRAL MASKS DURING THE COVID-19 PANDEMIC
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Matthieu SOLLOGOUB at ICS 20
  • Application of cyclodextrin containing sliding-ring polymers in oil-well cement
  • Mallinckrodt gave up further development of adrabetadex (VTS-270; HPBCD)
  • GRAS status of CD derivatives
  • How air fresheners work?

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