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Tag: anesthesia

August 18, 2025 CD as API / CD derivatives / Pharma applications

Results of Phase III clinical trial on efficacy and safety of Adamgammadex

This multicentre, randomised, double-blind, positive-controlled, noninferiority phase III clinical trial aimed to investigate the efficacy and safety of adamagammadex compared

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August 12, 2025 CD as API / Pharma applications

A Comparative Study of Sugammadex and Neostigmine: A Bibliometric Analysis of the Past 15 Years

 Sugammadex is a novel selective relaxant binding agent for aminosteroid neuromuscular blocking agents (NMBAs). However, existing literature reveals major knowledge

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April 17, 2023 CD as API / Uncategorized

Neostigmine vs. sugammadex: on postoperative nausea and vomiting (PONV) after general anaesthesia

Sugammadex (SGM) is the first cyclodextrin derivative approved as an API, the result of a rational drug design, with a

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September 28, 2021 CD as API / Pharma applications

Comparison of Selective Relaxant Binding Agent Adamgammadex Sodium with Sugammadex for Reversing Rocuronium-Induced Deep Neuromuscular Block

Zhao et al. reported on a phase IIa, single-center, randomized, open-label, and dose-finding study that enrolled 35 patients under general

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July 2, 2021 Drug delivery / Pharma applications

Improvement of Butamben Anesthetic Efficacy by the Development of Deformable Liposomes Bearing the Drug as Cyclodextrin Complex

This work was aimed at enhancing butamben (BTB) anesthetic efficacy by the “drug-in cyclodextrin (CD)-in deformable liposomes” strategy. In the

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May 13, 2019 Drug delivery / Pharma applications

The Use of ADV6209 for Premedication in Pediatric Anesthesia

A recently posted phase 2 clinical trial (not yet recruiting) aims to evaluate the effect of ADV6209, a new oral

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Top Posts

  • Methyl salicylate/methyl-β-cyclodextrin inclusion complex modulates plant defense against cold and heat stress
  • CDs as Modulators of Regulated Cell Death: Implications for Immunometabolism and Therapeutic Innovation
  • Recent Advances in Intranasal Administration for Brain-Targeting Delivery
  • The story of cyclodextrin metal–organic frameworks and their applications from Nobel-prize laureate, F. Stoddart
  • Improving Drug Bioavailability with Cyclodextrin Complexes: An integrative meta-modeling approach
  • Innovative Cyclodextrin Composition for Canine Odour Neutralization
  • Lanosterol eye drops for cataract treatment
  • One-pot synthesis of γ-cyclodextrin of high purity from non-food cellulose without the use of complexing agents
  • Hybrid Cyclodextrin Nanosponges Meet Nanoporous Gold: A Step Forward in Sensing Platforms
  • Three Birds, One Excipient: Development of an Improved pH, Isotonic, and Buffered Ketamine Formulation for Subcutaneous Injection

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