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Tag: Alzheimer’s disease

January 27, 2026 CD as API / Pharma applications

A water-soluble β-cyclodextrin polymer reduces cholesterol accumulation and autophagy dysfunction in vitro and in Niemann-Pick type C disease model mice

A β-CDP (CycloLab) was used for the experiments. The purity of the β-CDP was >95 %. The β-CDP contained <1 % of

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November 17, 2025 CD as API / Pharma applications

Cyclodextrins as Active Therapeutic Agents: Beyond Their Role as Excipients

Cyclodextrins (CDs) have traditionally been recognized as excipients that enhance solubility and stability of drugs. However, growing evidence shows that

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March 13, 2025 CD as API / Pharma applications / Uncategorized

CD treatment against cellular senescence

Cellular senescence, a hallmark of aging, has been implicated in Alzheimer’s disease (AD) pathogenesis. Cholesterol accumulation is known to drive

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December 17, 2024 Drug delivery / Pharma applications / Uncategorized

Multi Targeted Therapy for Alzheimer’s Disease by Guanidinium-Modified Calixarene and Cyclodextrin Co-Assembly Loaded with Insulin

Amyloid-β (Aβ) is considered a primary therapeutic target for Alzheimer’s disease (AD). However, just eliminating Aβ in patients with AD

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December 11, 2024 CD as API / Pharma applications

Alzheimer’s disease drug development pipeline: 2024

New therapies to prevent or delay the onset of symptoms, slow progression, or improve cognitive and behavioral symptoms of Alzheimer’s

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December 10, 2024 CD as API / Drug delivery / Pharma applications

Alzheimer’s Disease as Type 3 Diabetes: Understanding the Link and Implications

Alzheimer’s disease (AD) and type 2 diabetes mellitus (T2DM) are two prevalent conditions that present considerable public health issue in

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November 6, 2024 CD as API / Pharma applications

More and more manipulated results in Alzheimer and Parkinson’s research

 „Short road to discovery, winding road to use”                                                                                                 Josef Pitha I assume that many of you remember the “story”

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March 16, 2023 CD as API / CD derivatives / Life sciences / Pharma applications

Patent application: gamma-cyclodextrin-based polymer for prevention or treatment of cholesterol metabolism-related diseases

RENATUS, a South Korea-based pharma company pioneering next generation cyclodextrin-based therapies for the safe treatment of cholesterol-associated diseases recently filed

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November 18, 2022 CD as API / CD derivatives

Nature.com: HPBCD treatment improves learning and executive function in Alzheimer model mice

Earlier we have reported on a patent appication related to HPBCD treatment in Alzheimer’s disease based on the invention of

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September 29, 2022 CD as API / Life sciences / Uncategorized

MIT scientists filed patent for HPBCD treatment in Alzheimer’s disease

Li-Huei Tsai, director of Picower Institute for Learning and Memory (Massachusetts Institute of Technology) and her coworkers recently filed a patent

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