Cyclodextrin-Based Niosomal Delivery of Imatinib
Lung cancer remains a significant cause of cancer-related deaths globally. The effective cancer treatment aims to deliver drugs that specifically
Category: Drug delivery
pH-responsive magnetic cyclodextrin-liposome nanoplatforms for stabilization and targeted delivery of topotecan
Topotecan (TPT), a potent anticancer agent, suffers from rapid hydrolysis of its active lactone ring under physiological conditions, severely limiting
Cyclodextrin-Driven Drug Deaggregation
The poor aqueous solubility of niclosamide (Nic), a drug with broad therapeutic potential beyond its original antiparasitic use, presents a
Special Issue of the 21st International Cyclodextrin Symposium
The papers from the Special Issue of the 21st International Cyclodextrin Symposium published in Carbohydrate Polymers are available (https://www.sciencedirect.com/special-issue/10BLTS8S758). The
HPBCD in liquid formulations: a systematic study of physical properties and surfactant compatibility
The researchers of TEVA (USA) explored the role of 2-hydroxypropyl-β-cyclodextrin (HPβCD) as an excipient in liquid formulations by evaluating its
Neuroprotective effects of statins and cyclodextrins: review and potential role in dementia treatment
Dementia is a progressive and irreversible deterioration in cognition that has a significant impact on the person’s activities of daily
HPBCD and polysorbate containing formulation to eliminate aggregation of a potent osteogenic protein, recombinant human NELL-1
This study utilized a four-stage rational formulation development approach to mitigate aggregation and stabilize a high molecular weight protein, rhNELL-1.
A host-guest mediated immunomodulatory hydrogel with sustained antibacterial activity for healing of infected diabetic wounds
To solve the hinderance of infected diabetic wound regeneration and healing, an antibacterial and immunomodulatory hydrogel based on host-guest mediated
Fungal quorum sensing molecules as potential drugs in the treatment of chronic wounds and their delivery
Interestingly fungal quorum sensing signal molecules (QSMs) were found effective against bacterial biofilms hindering the healing of chronic non-healing wounds
Novel delivery systems for Resveratrol
A novel polymer, β-cyclodextrin-epichlorohydrin-cyanoguanidine polymer (CDPC) was synthesized to evaluate its potential as an efficient carrier for the encapsulation of