Cyclodextrin-assisted drug delivery to Central Nervous System: Mavenclad™ for multiple sclerosis treatment
In a recent study, Professors Bodor and Buchwald review the use of cyclodextrin-enabled formulations to develop oral tablets of cladribine
Category: Drug delivery
Carvone derived cannabidiol enantiomers as novel anticonvulsants
Developmental epilepsy syndromes are characterized by recurrent seizures and developmental delays. Current anticonvulsants target γ-aminobutyric acid type A receptor signaling
Polyphenols’ encapsulation in cyclodextrins: An updated systematic literature review
Polyphenols are phytochemicals derived from fruits, leaves, flowers, roots, and other parts of various plants and other natural resources. These
Cyclodextrin complexation of selected tyrosine kinase inhibitors
The comprehensive physicochemical characterization and cyclodextrin complexation of four tyrosine kinase inhibitors — erlotinib, gefitinib, vandetanib, and lapatinib — were
Cyclodextrin-in-Liposome for therapy: Advances and challenges
The concept of drug-in-cyclodextrin-in-liposomes (DCLs) was introduced to the scientific community thirty years ago by McCormack and Gregoriadis (1994). Since
Thymol/gallic acid/β-cyclodextrin bio-nanocomposite against quorum sensing system and biofilm formation in P. aeruginosa (PAO1)
The quorum sensing (QS) system and cell-to-cell communication have had a significant impact on biofilm formation and virulence factor increase
Cyclodextrin-Based Supramolecular Hydrogels in Therapy
Injectable biopolymer-based hydrogels have emerged as a powerful class of biomaterials designed for minimally invasive therapeutic strategies in modern medicine.
Effects on LuxR-Regulated Bioluminescence of Cyclodextrin-Acyl-L-Homoserine Lactone Hybrids
In this work, acyl homoserine lactones (AHLs) were grafted, the most studied signaling molecules in many Gram-negative bacteria, onto cyclodextrins
Gamma-cyclodextrin as molecular chaperone in protein delivery and stabilization
The interaction of a small, monomeric cytoplasmic protein, Cellular retinoic acid binding protein I (CRABPI), with cyclodextrins (α-, β-, and
Launch of KLEPTOSE® Crysmeb Methyl-Beta-Cyclodextrin for Oral and Parenteral Formulations
Roquette {oosts Extensive Cyclodextrins Portfolio with Launch of KLEPTOSE® Crysmeb Methyl-Beta-Cyclodextrin for Oral and Parenteral Formulations In contrast to DIMEB