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Tag: nasal delivery

August 6, 2025 Drug delivery / Pharma applications / Uncategorized

Development of a nasal spray based on cyclodextrin/hydrophobically-modified hydroxypropyl-methyl cellulose for the prevention of viral respiratory infections

The work aims to develop mucoadhesive and thermo-responsive in situ gelling systems, using hydrophobically-modified hydroxypropyl-methyl cellulose (Sangelose, SG) and beta-cyclodextrin

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February 25, 2025 Drug delivery / Pharma applications

Possible treatment of brain tuberculosis by methyl-β-cyclodextrin–assisted trans-nasal delivery of anti-tuberculosis drugs

Tuberculosis (TB) is prevalent worldwide. One of the most life-threatening manifestation of extrapulmonary tuberculosis is the involvement of central nervous

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October 2, 2024 Drug delivery / Pharma applications

An overview of in vitro and in vivo techniques for characterization of intranasal protein and peptide formulations for brain targeting

The surge in neurological disorders necessitates innovative strategies for delivering active pharmaceutical ingredients to the brain. The non-invasive intranasal route

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March 26, 2024 Drug delivery / Pharma applications

Recent Advances in Intranasal Administration for Brain-Targeting Delivery

Addressing disorders related to the central nervous system (CNS) remains a complex challenge because of the presence of the blood-brain

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March 18, 2024 CD as API / Drug delivery / Pharma applications

Advances in Ferroptosis-Inducing Agents by Targeted Delivery System in Cancer Therapy

Ferroptosis is a regulated cell death process caused by lipid peroxidation of membrane unsaturated fatty acids catalyzed by iron ions

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August 25, 2021 Drug delivery / Pharma applications

Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

Quercetin, a flavonoid with possible neuroprotective action has been recently suggested for the early-stage treatment of Alzheimer’s disease. The low

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June 3, 2021 CD as API / CD derivatives / Pharma applications

Nitric oxide and COVID-19

A clinical trial in United Kingdom confirms SaNOtize’s breakthrough treatment for COVID-19 SaNOtize R. & D. Corp, a Canadian Biotech

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October 13, 2020 Drug delivery / Pharma applications

Nasal administration of COVID-19 vaccine

Researchers lead by Professor Michael S. Diamond at Washington University School of Medicine in St. Louis, have developed a COVID-19

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February 14, 2020 Drug delivery / Pharma applications

Nasal delivery with beta-cyclodextrin is approved; a short story of Baqsimi

Cyclodextrins have not been popular excipients for nasal or pulmonary drug delivery so far. This can change soon, with the

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