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Tag: foam cells

a rat is standing on top of a plastic container
December 18, 2025 CD as API / CD derivatives / Pharma applications

Selective removal of 7-ketocholesterol by a CD-dimer, a novel atherosclerosis therapeutic candidate

The removal of the toxic oxidized cholesterol, 7-ketocholesterol (7KC), from cells through the administration of therapeutics has the potential to

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September 28, 2023 CD as API / Drug delivery / Pharma applications

Biomimetic nanoparticles to enhance the reverse cholesterol transport for selectively inhibiting development into foam cell in atherosclerosis

A disorder of cholesterol homeostasis is one of the main initiating factors in the progression of atherosclerosis (AS). Metabolism and

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October 7, 2022 CD as API / Pharma applications / Supramolecular systems

Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis

A promising therapy for atherosclerosis treatment was designed by targeting LXR receptor (LXR) on atherosclerotic macrophage, where LXR activation could

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