Cyclodextrins in oral formulations – has the time of supergenerics come?
Development of generic formulations with cyclodextrins for oral delivery has been neglected for several decades, since the CD-enabled formulations often
Category: Drug delivery
Amgen Submits Supplemental New Drug Application For KYPROLIS® (carfilzomib)
Amgen announced on the 27th August, 2018 the submission of a supplemental New Drug Application (sNDA) to the U.S. Food
Cyclodextrin-containing polymer-camptothecin nanopharmaceutical. Clinical trials
Cyclodextrin-containing polymer (CDP) (represented by blue in the scheme) conjugated to camptothecin (CPT) (represented by red) forms 30-40-nm diameter nanoparticles
Cyclodextrin to formulate proteins – dream or reality
Several cyclodextrins have been claimed by dozens of papers including huge works of Serno [1] and Hartl [2] to be
Video-class on the effect of cyclodextrins on drug permeation through membranes
Prof. Thorsteinn Loftsson (University of Iceland) explains in his lecture on the website of CyclonHit project the mechanism how drugs
Video-class on the Effects of Cyclodextrins on Drug Stability
The video of Prof. Thorsteinn Loftsson on the website of CyclonHit project gives the basic information on the effect of
Video-class on Cyclodextrins as Solubilizers
The video of Prof. Thorsteinn Loftsson shows how to perform solubility studies, the types of phase-solubility isotherms, continuous variation plots
Video-class on Pharmacokinetics, Toxicology and Regulatory Status of Cyclodextrins
The video of Prof. Thorsteinn Loftsson on the website of CycloHit project gives a summary on the physicochemical and pharmacokinetic
Cyclodextrins at CPHI Worldwide
The biggest pharma exhibition in the world, CPHI Worldwide will be organized 9-11th October in Madrid. By joining (which is
AAPS Pharmsci 360 – exhibition and conference combined (4-7th November)
For those, interested in building relationships with industrial partners as well as broadening their knowledge in state-of-the-art academic research, AAPS