Lessons from space studies on stability of a drug / cyclodextrin composition
Assessing the stability of drugs in space is crucial for future missions due to various environmental factors such as radiation,
Category: Drug delivery
FDA grants approval to Axsome Therapeutics’ migraine medication containing Betadex Sulfobutylether Sodium
The U.S. Food and Drug Administration has approved Axsome Therapeutics’ new migraine treatment tablet on 30 January 2025 [1]. Marketed
Cyclodextrins unlock the full potential of lipopeptides — reducing cytotoxicity while keeping their antimicrobial efficacy intact
Over the past decade, the growing threat of antibiotic resistance has intensified interest in antimicrobial peptides and lipopeptides as promising
Cyclodextrin-based iodophors with high iodine retention in solid state and in dilute solutions
Iodine is a broad-spectrum antiseptic with the advantage of not inducing bacterial resistance, but its use is limited by volatility.
Aqueous eye drop formulations: Cyclodextrins as enabling excipients
Cyclodextrins are enabling pharmaceutical excipients that solubilize and stabilize drugs in aqueous formulations. Cyclodextrins possess very favorable pharmacokinetic and toxicological
Hydroxypropyl β Cyclodextrins Effects on Self-Assembly of Cyclic Peptide, Lanreotide Acetate, in Water and Subsequent Release rate from an in vitro Emulator of Subcutaneous Delivery
Most of peptide drugs are often delivered subcutaneously. The significant barrier in this type of peptide administration is the high
Enhancing Cannabinoid Bioavailability in Pain Management: The Role of Cyclodextrins
Chronic pain (CP), including pain related to cancer, affects approximately 2 billion people worldwide, significantly diminishing quality of life and
Winners of 2024 Lasker-DeBakey Clinical Medical Research Award for their pioneering works on GLP-1-based therapy for obesity
This year Lasker-De Bakey Clinical Medical Research Award honoured three scientists for their discovery and development of glucagon-like peptide-1 (GLP-1)-
Quercetin: A Flavonoid with Potential for Treating Acute Lung Injury
In intensive care units, acute lung injury (ALI) is a syndrome that is frequently encountered. It is associated with a
Clinical Effectiveness, Safety, and Compliance of Two Compounded Formulations of Tacrolimus Eye Drops: An Open-Label, Sequential Prospective Study
Ophthalmic tacrolimus compounded formulations are usually made from the commercial intravenous presentation, which contains ethanol as a solubilizer due to