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June 30, 2023 Drug delivery / Pharma applications

Cyclodextrin-containing drugs among top 200 Brand Name Drugs by retail sales

A recent poster by R.E. Williams and C. M. Marshall, (Jon Njardarson’s group, University of Arizona) listed the Top 200

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June 22, 2023 CD as API / Pharma applications

Serving patient’s safety and comfort: Effects of sugammadex vs. neostigmine on postoperative nausea, vomiting and pulmonary complications following general anesthesia.

A recent study published by Korean scientists compared the effect of sugammadex with that of neostigmine in terms of the

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June 14, 2023 CD as API / CD derivatives / Pharma applications

A sugammadex-analogue, per-6-O-carboxyhexyl-thio-gamma-CD (OKL-1111) is a highly potent and universal reversal agent for anticoagulants

Antithrombotic therapy is undoubtedly associated with a risk for bleeding and these bleeding complications sometimes can be life-threatening. Recently, specific

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April 5, 2023 Other industrial use

Cyclodextrins to control bacteriophages infection in biotechnology

In the biotechnology industry one of the biggest threats for bacteria-driven bioreactors is the infections caused by enemies of bacteria,

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March 6, 2023 Drug delivery / Pharma applications

Cyclodextrin-enabled nepafenac eye drops with improved absorption

Nepafenac is a highly effective NSAID used for treating postoperative ocular inflammation and pain after cataract surgery and its advantage

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February 10, 2023 Drug delivery / Pharma applications

Oral Xenon/alpha-Cyclodextrin Provides Neuroprotection for Ischemic Stroke

Ischemic stroke is one of the main causes of long-term morbidity/mortality and early treatment of stroke is key issue. Xenon

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December 1, 2022 CD as API / Pharma applications

Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?

In this review, based on 250 references, the general chemical principles of direct cyclodextrin–protein interactions are summarized and highlighted, through

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October 26, 2022 Drug delivery / Pharma applications

Pharmacokinetic study of sulfobutylether beta-cyclodextrin as an excipient of remdesivir

SBECD (Captisol®) with an average degree of substitution of 6.5 sulfobutylether functional groups (SBE = 6.5), is a solubility enhancer

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June 29, 2022 Events / Non-pharma applications / Pharma applications

Special issue: Recent Insights in Chemistry and Technology of Cyclodextrins

International Journal of Molecular Sciences (MDPI) plans a Special Issue: Recent Insights in Chemistry and Technology of Cyclodextrins in connection

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June 22, 2022 Events

2022 Szejtli prize to Angela Scala

The CycloLab’ Szejtli award committee, has decided to award the 2022 Szejtli prize, to Dr Angela Scala, Associate Professor of

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Recent Posts

  • Special issue: “Synthesis, Analysis and Applications of Cyclodextrins and Their Derivatives”
  • Multiscale mechanistic analysis of reversible cross-linking polymers based on host–guest interactions
  • Redox responsive cyclodextrin-based drug delivery systems: a special insight to glutathione responsive CD-nanosponges
  • CD in prevention of dengue-induced lethality
  • A Bubble-Driven Drug Delivery System Enhances Oral Absorption and Antipyretic Efficacy of Poorly Water-Soluble Andrographolide

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Top Posts

  • Special issue: “Synthesis, Analysis and Applications of Cyclodextrins and Their Derivatives”
  • New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA
  • Clinical trial: Safety, Efficacy and Pharmacokinetics of CBT-006 in Patients With Meibomian Gland Dysfunction
  • Recent papers on Cyclodextrins in Nature
  • Antibody conjugated cyclodextrin for tumor drug delivery
  • Sustainable capture and photocatalytic degradation of organic pollutants by high-swelling cyclodextrin polymer loaded with TiO2 nanoparticles
  • Lanosterol eye drops for cataract treatment
  • MIT scientists filed patent for HPBCD treatment in Alzheimer's disease
  • Pharmacokinetic study of sulfobutylether beta-cyclodextrin as an excipient of remdesivir
  • Surface-Engineered Amino-Graphene Oxide Aerogel Functionalized with Cyclodextrin for Desulfurization and Denitrogenation in Oil Refining

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