Posted by In recent decades, the biomedical and pharmaceutical potential of cyclodextrins has expanded remarkably. Their well‑established host–guest complexation ability continues to play a key role in enhancing the solubility and therefore the bioavailability of poorly soluble, lipophilic small‑molecules. At the same time, cyclodextrins and their polymeric derivatives have increasingly been applied in the formulation of larger biomolecules, including peptides and nucleic acids.
Beyond their formulation benefits, the intrinsic biological activities of cyclodextrins have become an area of growing scientific interest. Far from being inactive excipients, these molecules exhibit properties that may be harnessed in diverse biomedical contexts, such as infectious disease research, cardiovascular therapy, and the study of cholesterol‑associated neurodegenerative disorders.
This Special Issue in Pharmaceutics aims to present the latest advances in cyclodextrin‑based delivery systems, covering host–guest interactions, innovative dosage forms, and emerging insights into their biological effects. We welcome reviews and original research articles.
Dr. Ágnes Rusznyák
Dr. Ferenc Fenyvesi
Guest Editors
https://www.mdpi.com/journal/pharmaceutics/special_issues/819259P2H5