CD-based radial polycatenanes were prepared in one-pot through polypseudorotaxane formation between β-CD and thiolated pluronic and subsequent cyclization via disulfide bonds. However, no reports are available on syntheses of CD polycatenane derivatives. The disulfide bonds are not stable enough to synthesize CD polycatenane derivatives; therefore, a chemically stable β-CD polycatenanewas prepared via amide bond through cyclization of β-CD/aminated pluronic polypseudorotaxane with terephthaloyl chloride. This allowed the derivatization of the polycatenane owing to its stable chemical structure, and resulted in the syntheses of three different water soluble polycatenane derivatives: aminated, succinylated, and hydroxypropylated polycatenanes. These findings may provide useful information for the fabrication of polycatenane-based materials such as slide-ring materials, drug carriers, and biomaterials.
Morita, K., Motoyama, K., Kuramoto, A, Onodera, R., Higashi, T. Synthesis of cyclodextrin‐based radial polycatenane cyclized by amide bond and subsequent fabrication of water‐soluble derivatives. J Incl Phenom Macrocycl Chem 100, 169–175 (2021). https://doi.org/10.1007/s10847-021-01068-4