Nanoemulsions, which are characterized by their nanometer-scale droplets, have gained significant attention in different fields, such as medicine, food, cosmetics, and agriculture, because of their unique properties. With an increasing number of countries engaging in research on nanoemulsions, interest in their properties, preparation methods, and applications has increased. Hence, tracing the relevant research on nanoemulsions published in the past ten years on a global scale, by conducting data mining and visualization analysis on a sufficiently large text dataset through bibliometrics.
Nanoemulsions are two immiscible liquids with droplet diameters between 20 nm and 500 nm that are mixed and stabilized via suitable emulsifiers to create a two-phase dispersion system, including two-phase systems such as O/W and W/O nanoemulsions, as well as multiple nanoemulsions such as W/O/W.
Compared with lipid nanoparticles, nanoemulsions can better overcome the blood‒brain barrier, exhibit good cell viability and transfection efficiency, and have greater diffusion properties.
The following CD-related examples are mentioned:
- nanoemulsions containing cinnamon essential oil encapsulated in beta-cyclodextrin and sodium caseinate, resulting in a longer storage time
- edible cyclodextrin-based MOF stabilized by glycyrrhizic acid
Sun G, Wang L, Dong Z, Zhang Y, Yang Y, Hu M, Fang H. The Current Status, Hotspots, and Development Trends of Nanoemulsions: A Comprehensive Bibliometric Review. Int J Nanomedicine. 2025;20:2937-2968
https://doi.org/10.2147/IJN.S502490
Featured image credit to Mustafa, I.F.; Hussein, M.Z. https://doi.org/10.3390/nano10081608